Liver scan using radioactive 198Au-Colloid, detection of HBsAg by 125I RIA kit and measuring of serum AFP by 1251 RIA kit were done on the 122 primary hepatic carcinoma patients and 83 nonmalignant hepatic diseases and normal subjects, who were diagnosed and treated at the Department of Internal Medicine, CNU Hospital since Apr, 1980 to Apr. 1981.
The results were analyzed in the aspect of diagnostic significance as follows.
1. The size of cold area on the liver scan were in 5-10cm in diameter in .54.1%of the primary hepatoma, and the location of cold area were on the right lobe of the liver in 72. 1 % of the cases.
2. The HBsAg were positive in 66.2% of the primary hepatoma and there was no significant difference between the size of cold area and the positive rate of HBsAg.
3. The serum AFP were elevated above normal in 56.6% of primary hepatoma and in 76.5% of those cases, the serum AFP were over 200 ng/ml.
The serum AFP levels were also elevated in acute and chronic hepatitis, liver cirrhosis in the range of 19. 2%~37.5% of the cases but the level of serum AFP were not so high as in the primary hepatoma.
4. There was no significant relationship between the size of cold area and the level of serum AFP in primary hepatoma.
5. There were no significant relationships between the size of cold area, the level of serum AFP and the level of serum Alkaline Phosphates in the primary hepatoma.
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